Scleroderma is an auto-immune disease. There are many auto-immune diseases, such as multiple sclerosis, rheumatoid arthritis, and many others. Scleroderma is a group of progressive and rare diseases that comprise the tightening and hardening of the skin as well as connective tissues – the fibers that provide the support and framework for the body.
Localized scleroderma upsets only the skin. Systemic scleroderma can also harm internal organs such as the lungs, heart, digestive tract as well as kidneys.